Impact of ICU-acquired weakness on post-ICU physical functioning: a follow-up study

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Impact of ICU-acquired weakness on post-ICU physical functioning: a follow-up study

INTRODUCTION ICU-acquired weakness is thought to mediate physical impairments in survivors of critical illness, but few studies have investigated this thoroughly. The purpose was to investigate differences in post-ICU mortality and physical functioning between patients with and without ICU-acquired weakness at 6 months after ICU discharge. METHOD ICU patients, mechanically ventilated ≥ 2 days...

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A pilot observational study by Weber-Carstens and colleagues contributes to a mechanistic explanation of the puzzling and complex phenomena of ICU-acquired weakness (ICU-AW). The authors suggest systemic, inflammatory-mediated pathology is the most significant risk factor for ICU-AW. While this finding is somewhat equivocal, it provides important direction for future investigations and illustra...

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Copyright © 2014 Massachusetts Medical Society. W eakness acquired in the intensive care unit (ICU) is caused by many different pathophysiological mechanisms that are not mutually exclusive. This is not surprising, given the diverse diseases that precipitate critical illness, the drugs used during its management, and the consequences of protracted immobility. Nonetheless, conceptualization of t...

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ژورنال

عنوان ژورنال: Critical Care

سال: 2015

ISSN: 1364-8535

DOI: 10.1186/s13054-015-0937-2